Wavelet analysis of Jones-matrix images corresponding to polycrystalline networks of biological crystals in diagnostics of tuberculosis

Determined in this work are analytical interrelations between orientations of optical axes and birefringence of biological crystals as well as characteristic values of elements in the Jones matrix for flat layers of polycrystalline networks, which determine conditions for formation of polariza...

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Дата:2011
Автори: Zabolotna, N.I., Balanetska, V.O., Telenga, O.Yu., Ushenko, V.O.
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Мова:English
Опубліковано: Інститут фізики напівпровідників імені В.Є. Лашкарьова НАН України 2011
Назва видання:Semiconductor Physics Quantum Electronics & Optoelectronics
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Цитувати:Wavelet analysis of Jones-matrix images correspondingto polycrystalline networks of biological crystals in diagnostics of tuberculosis / N.I. Zabolotna, V.O. Balanetska, O.Yu. Telenga, V.O. Ushenko // Semiconductor Physics Quantum Electronics & Optoelectronics. — 2011. — Т. 14, № 2. — С. 228-236. — Бібліогр.: 31 назв. — англ.

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spelling irk-123456789-1177132017-05-27T03:04:03Z Wavelet analysis of Jones-matrix images corresponding to polycrystalline networks of biological crystals in diagnostics of tuberculosis Zabolotna, N.I. Balanetska, V.O. Telenga, O.Yu. Ushenko, V.O. Determined in this work are analytical interrelations between orientations of optical axes and birefringence of biological crystals as well as characteristic values of elements in the Jones matrix for flat layers of polycrystalline networks, which determine conditions for formation of polarization singularities in laser images. Performed is a complex statistical, correlation and fractal analysis of distributions for the amount of characteristic values inherent to the Jones matrix elements describing layers of saliva taken from a healthy patient and that sick with tuberculosis. The authors have ascertained objective criteria to differentiate optical properties of polycrystalline networks of human saliva in various physiological states. Offered is Jones-matrix diagnostics of tuberculosis. 2011 Article Wavelet analysis of Jones-matrix images correspondingto polycrystalline networks of biological crystals in diagnostics of tuberculosis / N.I. Zabolotna, V.O. Balanetska, O.Yu. Telenga, V.O. Ushenko // Semiconductor Physics Quantum Electronics & Optoelectronics. — 2011. — Т. 14, № 2. — С. 228-236. — Бібліогр.: 31 назв. — англ. 1560-8034 PACS 33.50.-j, 34.35.+a, 73.20.Mf, 78.30.-j http://dspace.nbuv.gov.ua/handle/123456789/117713 en Semiconductor Physics Quantum Electronics & Optoelectronics Інститут фізики напівпровідників імені В.Є. Лашкарьова НАН України
institution Digital Library of Periodicals of National Academy of Sciences of Ukraine
collection DSpace DC
language English
description Determined in this work are analytical interrelations between orientations of optical axes and birefringence of biological crystals as well as characteristic values of elements in the Jones matrix for flat layers of polycrystalline networks, which determine conditions for formation of polarization singularities in laser images. Performed is a complex statistical, correlation and fractal analysis of distributions for the amount of characteristic values inherent to the Jones matrix elements describing layers of saliva taken from a healthy patient and that sick with tuberculosis. The authors have ascertained objective criteria to differentiate optical properties of polycrystalline networks of human saliva in various physiological states. Offered is Jones-matrix diagnostics of tuberculosis.
format Article
author Zabolotna, N.I.
Balanetska, V.O.
Telenga, O.Yu.
Ushenko, V.O.
spellingShingle Zabolotna, N.I.
Balanetska, V.O.
Telenga, O.Yu.
Ushenko, V.O.
Wavelet analysis of Jones-matrix images corresponding to polycrystalline networks of biological crystals in diagnostics of tuberculosis
Semiconductor Physics Quantum Electronics & Optoelectronics
author_facet Zabolotna, N.I.
Balanetska, V.O.
Telenga, O.Yu.
Ushenko, V.O.
author_sort Zabolotna, N.I.
title Wavelet analysis of Jones-matrix images corresponding to polycrystalline networks of biological crystals in diagnostics of tuberculosis
title_short Wavelet analysis of Jones-matrix images corresponding to polycrystalline networks of biological crystals in diagnostics of tuberculosis
title_full Wavelet analysis of Jones-matrix images corresponding to polycrystalline networks of biological crystals in diagnostics of tuberculosis
title_fullStr Wavelet analysis of Jones-matrix images corresponding to polycrystalline networks of biological crystals in diagnostics of tuberculosis
title_full_unstemmed Wavelet analysis of Jones-matrix images corresponding to polycrystalline networks of biological crystals in diagnostics of tuberculosis
title_sort wavelet analysis of jones-matrix images corresponding to polycrystalline networks of biological crystals in diagnostics of tuberculosis
publisher Інститут фізики напівпровідників імені В.Є. Лашкарьова НАН України
publishDate 2011
url http://dspace.nbuv.gov.ua/handle/123456789/117713
citation_txt Wavelet analysis of Jones-matrix images correspondingto polycrystalline networks of biological crystals in diagnostics of tuberculosis / N.I. Zabolotna, V.O. Balanetska, O.Yu. Telenga, V.O. Ushenko // Semiconductor Physics Quantum Electronics & Optoelectronics. — 2011. — Т. 14, № 2. — С. 228-236. — Бібліогр.: 31 назв. — англ.
series Semiconductor Physics Quantum Electronics & Optoelectronics
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AT telengaoyu waveletanalysisofjonesmatriximagescorrespondingtopolycrystallinenetworksofbiologicalcrystalsindiagnosticsoftuberculosis
AT ushenkovo waveletanalysisofjonesmatriximagescorrespondingtopolycrystallinenetworksofbiologicalcrystalsindiagnosticsoftuberculosis
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fulltext Semiconductor Physics, Quantum Electronics & Optoelectronics, 2011. V. 14, N 2. P. 228-236. PACS 33.50.-j, 34.35.+a, 73.20.Mf, 78.30.-j Wavelet analysis of Jones-matrix images corresponding to polycrystalline networks of biological crystals in diagnostics of tuberculosis N.I. Zabolotna1, V.O. Balanetska2, O.Yu. Telenga3, V.O. Ushenko3 1Vinnytsia National Technical University, Department for Laser and Optoelectronic Technique, 95, Khmelnytske shose, 21021 Vinnytsia, Ukraine. 2Bukovina State Medical University, Department of Biophysics and Medical Informatics, 2, Teatralnaya Sq., 58012 Chernivtsi, Ukraine. 3Chernivtsi National University, Department for Optics and Spectroscopy, 2, Kotsyubinsky str., 58012 Chernivtsi, Ukraine. Abstract. Determined in this work are analytical interrelations between orientations of optical axes and birefringence of biological crystals as well as characteristic values of elements in the Jones matrix for flat layers of polycrystalline networks, which determine conditions for formation of polarization singularities in laser images. Performed is a complex statistical, correlation and fractal analysis of distributions for the amount of characteristic values inherent to the Jones matrix elements describing layers of saliva taken from a healthy patient and that sick with tuberculosis. The authors have ascertained objective criteria to differentiate optical properties of polycrystalline networks of human saliva in various physiological states. Offered is Jones-matrix diagnostics of tuberculosis. Keywords: laser, polarization, birefringence, Jones matrix, statistical moments, autocorrelation, power spectrum, tuberculosis. Manuscript received 04.07.11; accepted for publication 16.03.11; published online 30.06.11. 1. Introduction 7 © 2011, V. Lashkaryov Institute of Semiconductor Physics, National Academy of Sciences of Ukraine 1.0 Among the methods of optical diagnostics aimed at biological tissues (BT), the methods of laser polarimetry of optically anisotropic structures in human tissues have been already widely spread [1 – 31]. The main “information product” of using these methods is data for coordinate distributions inherent to Mueller and Jones matrixes typical for BT [1 – 5]. Then, these data can be processed with statistical (statistical moments of the first to fourth orders [5, 6, 10, 14, 19, 25, 26, 30]), correlation (auto- and mutual-correlation functions [12, 17, 18, 21, 26]), fractal (fractal dimensionalities [5, 6, 25]), singular (distributions of amounts of linear and circularly polarized states), wavelet (sets of wavelet coefficients for various scales of biological crystals [22, 28]) analyses. As a result, one can determine interrelations between a set of these parameters and distributions of optical axis directions as well as the birefringence value inherent to networks of optically single-axis protein (myosin, collagen, elastin, etc.) fibrils in optically anisotropic components of BT layer. Being based on it, developed was a set of methods for diagnostics and differentiation of pathological changes in BT structure, which are related with its degenerative-dystrophic and oncological changes [4 - 6, 12, 19, 20-22, 27, 29, 31]. Progress in the above methods for studying the matrix images of BT was reached in [5]. There, the offered new approach is based on the analysis of coordinate distributions for the so-called “characteristic values” that describe conditions for formation of polarization singularities. Related to these singularities are linear (L- points) and circularly (C-points) polarized states. In the case of L-points, the direction of electric field vector rotation is indefinite (singular). For C-points, indefinite is the azimuth of polarization for the electric field vector. Demonstrated in […] was the efficiency of this approach for Mueller-matrix diagnostics of pathological states in human BT. At the same time, there is a widely spread group of optically anisotropic biological objects, for which the matrix methods of laser polarimetric diagnostics did not yet acquire any wide application. These are optically thin (extinction coefficient ≤τ ) layers of various biological liquids (bile, urine, liquor, joint fluid, blood plasma, saliva, etc.). These objects are considerably more accessible for direct laboratory analysis as compared with traumatic methods of BT biopsy. Being based on these reasons, it seems topical to adapt the methods of laser polarimetric diagnostics of optically anisotropic structures observed in BT polycrystalline networks for medical purposes. 228 Semiconductor Physics, Quantum Electronics & Optoelectronics, 2011. V. 14, N 2. P. 228-236. Bearing in mind diagnostics of tuberculosis, our work is aimed at searching possibilities to diagnose and differentiate optical properties of liquid-crystal networks in human saliva by using determination of coordinate distributions for Jones-matrix elements with the following wavelet analysis of distributions inherent to their characteristic (singular) values. 2. Main analytical interrelations As a base for modeling the optical properties of liquid- crystalline networks in human saliva, we took the following conceptions [1-4, 7, 9, 14, 16, 23-27, 30]: • separate (partial) liquid crystals (…) are optically single-axis and birefringent; • optical properties of a partial crystal can be exhaustively described with the Jones operator [5] { } ( ) ( )[ ( )[ ] ( ) © 2011, V. Lashkaryov Institute of Semiconductor Physics, National Academy of Sciences of Ukraine ] . ;expcossin;exp1sincos ;exp1sincos;expsincos 22 22 2221 1211 δ−ρ+ρδ−−ρρ δ−−ρρδ−ρ+ρ == ii ii JJ JJ J (1) Here, is a direction of the optical axis; ρ ndΔλ π=δ 2 – phase shift between orthogonal components and of the amplitude of illuminating laser wave with the wavelength xE yE λ ; nΔ - birefringence index of the crystal with the geometric size . d Let us consider the possibility to apply the singular approach in the Jones-matrix images. From the mathematical viewpoint, a singular value of a matrix element complex value is defined by the following conditions: ikJ ( ) ( ) ⎪ ⎪ ⎩ ⎪⎪ ⎨ ⎧ = = =+ .0Im ;0Re ;0ImRe 22 ik ik ikik J J JJ (2) With account of (2), the analytical expressions (1) are transformed to interrelations ⎪⎩ ⎪ ⎨ ⎧ =δρ+ρ =δρ ⇔ .0cossincos ;0sinsin 22 2 11J , (3) ⎪⎩ ⎪ ⎨ ⎧ =δρ+ρ =δρ ⇔ .0coscossin ;0sincos 22 2 22J (4) ( ) ( )⎪⎩ ⎪ ⎨ ⎧ =δ+ρ =δ+ρρ⇔= .0cos12sin ;0cos1sincos2 22 2112 JJ (5) As it follows from (3) to (5), singularities of complex matrix elements are conditioned by certain (characteristic) values of orientation and phase parameters corresponding to liquid-crystalline network ∗ ikJ ∗ρ ∗δ ⎪⎩ ⎪ ⎨ ⎧ ±=δ ±=ρ ∗ ∗ .180;90;0 ;90;45;0 000 000 (6) On the other hand, the relations (6) determine the conditions for formation polarization singular states −L ( ) and 00 180;0=δ −C ( ) of the laser beam by optically single-axis birefringent crystal. Being based on it, one can find the characteristic values of the Jones matrix elements that define 090±=δ ∗ ikJ −L and states of polarization in a laser image of polycrystalline network: −C • 02211 == JJ values define states of polarization; −L • 02112 == JJ values define states of polarization. −C It is noteworthy that the analytical consideration of (1) to (6) is related to a partial optically single-axis birefringent crystal. Formed in real biological layers are complex networks of these crystals with different scales of geometric sizes. Therefore, application of the singular analysis to the Jones matrix corresponding to this network requires determining the coordinate distributions of characteristic values in the plane of biological liquid layer. These distributions can be determined by scanning two-dimensional arrays of elements in horizontal direction with the step ( yxJ ik ,∗ ) ikJ mx ...,,1≡ pixx 1=Δ . Within the limits of every local sampling (1pix × npix)(k = 1, 2, …, m), one has to calculate N characteristic values ( ) 0=kJik , - ( ( )k ikN ). In this manner, one finds dependences ( ) )...,,,( )()2()1( m ikikikik NNNxN ≡ of the amount of characteristic values for matrix elements. On the other hand, these multi-scale dependences can be efficiently analyzed using the wavelet analysis […]. If as a wavelet function one takes the dependence that possesses a finite base both in coordinate and frequency spaces, then using the scaling and shift of this function-prototype the coordinate distribution of Jones matrix elements can be expanded into the following series ∑ ∞ −∞= Ψ= ba ababik xCxN , )()( , (7) where )()( baxxab −Ψ=Ψ is the base function that is formed from the function-prototype using the shift b and scaling a, while the coefficients of this expansion are defined in the following manner ∫ Ψℵ= dxxxC abikab )()( (8) In our work, using the analogy with the investigation […], as a wavelet function we chose the second derivative of the Gauss function (MHAT wavelet) that possesses a narrow energy spectrum and 229 Semiconductor Physics, Quantum Electronics & Optoelectronics, 2011. V. 14, N 2. P. 228-236. two moments equal to zero (zero and first). The analytical dependence of the MHAT wavelet has the following look: 2/22/ 2 2 22 )1()( zz eze dz dz −− −==Ψ . (9) The result of wavelet transformation (9) is two- dimensional array of amplitudes or the sp ),( baW that in the space “spatial scale a – spatial localization b” provides information on relative contribution of birefringent network in crystals of different sca the dependence ( )xNik . Thus, it opens the possibility to realize a scale-selective analysis of real polycrystalline networks in various bio © 2011, V. Lashkaryov Institute of Semiconductor Physics, National Academy of Sciences of Ukraine Fig. 1. Optical scheme of the polarimeter: 1 – He-Ne laser; 2 – collimator; 3 – stationary quarter-wave plate; 5, 8 – mechanically movable quarter-wave plates; 4, 9 – polarizer and analyzer, respectively; 6 – studied object; 7 – micro-objective; 10 – CCD camera; 11 – personal computer. ectrum les to logical layers. ) 3. Optical setup for making Jones-matrix maps of optically anisotropic biological liquids Shown in Fig. 1 is the optical scheme of a polarimeter for measuring the coordinate distributions of elements in the Jones matrix corresponding to biological layers. Illumination of bile samples was carried out using a parallel beam (∅ = 104 µm) of the He-Ne laser (λ = 0.6328 µm, W = 5.0 mW). The polarization illuminator consists of the quarter-wave plates 3, 5 and polarizer 4, which provides formation of the laser beam with an arbitrary polarization state. Using the micro-objective 7 (magnification 4x), images of bile layers were projected onto the plane of light-sensitive area (800x600 pixels) in the CCD-camera 10 that provides measurements of structural elements from 2 to 2000 µm. The analysis of laser images was performed using the polarizer 9 and quarter-wave plate 8. 4. Criteria for estimating the spectra of wavelet coefficients corresponding to the amount of characteristic values inherent to Jones-matrix images describing the layers of human saliva Distributions of the amount of characteristic values for elements of the Jones matrix ),( baW ( nmJik × are characterized with the set of statistical moments of the 1- st to 4-th orders EAM ;;; σ calculated using the following relations [5, 6, 25, 30]: ( ) ( ) ( ) ( ) .),(11,),(11 ,),(1,),(1 1 4 4 1 3 3 1 2 1 ∑∑ ∑∑ == == σ = σ = =σ= D j j D j j D j j D j j baW D EbaW D A baW D baW D M (10) where is the number of pixels for which the dependence of characteristic values within the limits of coordinate distribution for Jones-matrix images of elements is determined. D ikN ikJ Our analysis of the spectra for wavelet coefficients in distributions was based on the autocorrelation method with using the following function [12, 21, 26]: ),( baW ( )xNik ( ) [ ][∫ Δ−÷==Δ m aa dbbbWxbW m bG 1 )()1(1 ] . (11) Here, bΔ is the “step” of changing the coordinate mbx ÷=≡ 1 . As to parameters characterizing the dependences ( )bG Δ , we chose the set of correlation moments from the 1-st to 4-th orders that are determined similarly to relations (10). 4;3;2;1=lK Estimating the degree of self-similarity and reproducibility for different geometric ( ) scales of the structure inherent to wavelet coefficients W of the distributions d ),( ba ( )xNik corresponding to characteristic values of the Jones-matrix elements ( )nmJik × describing the polycrystalline networks was performed via calculations of the logarithmic dependences for power spectra ( )[ ] )log(,log . These dependences are approximated using the least-squares method to curves 1−− dbaWJ ( )ηΦ . Straight-line parts of these curves enable us to determine the slope angles iη and calculate the values of fractal dimensionality for W distributions with account of the relations [5, 6, 11, 25]: ),( ba ii tggD η−= 3)( . (12) Classification of the distributions W for dependences of the amount of characteristic values ),( ba 230 Semiconductor Physics, Quantum Electronics & Optoelectronics, 2011. V. 14, N 2. P. 228-236. © 2011, V. Lashkaryov Institute of Semiconductor Physics, National Academy of Sciences of Ukraine typical for the matrix elements is carried out in accord with criteria offered in [5]. If the value of the slope angle ( nmJik × ) const=η , the dependences for 2 or 3 decades of changing the sizes d , than the distributions are fractal. Under condition that several constant slope angles are available in the curve ( )ηΦ a b Fig. 2. Polarization images of dendrite polycrystalline networks typical for human saliva in different physiological states. See explanations in the text. ),( baW ( )ηΦ , the sets are multi-fractal. When no stable slope angles are available over the whole interval of changing the sizes d , the sets are considered as random. ),( baW ),( baW To make this comparative analysis of dependences more objective, let us use the conception of spectral moments from the 1-st to 4-th orders - the relation (7). ( )[ ] )log(,balog 1−− dWJ ) 4;3;2;1=jS 5. Analysis and discussion of experimental results As objects of investigation, we used saliva smears of healthy (18 samples) and sick with tuberculosis (17 samples) patients. Fig. 2 shows laser images of optically- anisotropic structures typical for the samples of both types. The images were obtained for crossed transmission planes of the polarizer 4 and analyzer 9 in the laser polarimeter (Fig. 1). It can be seen from a comparative analysis of laser images corresponding to liquid-crystalline networks of the studied samples that the level of transmission (birefringence) grows in the case of small-scale (d = 10…30 µm) liquid crystals in saliva of the patients sick with tuberculosis (Fig. 2b). This fact was used as a basis for our wavelet analysis of the dependences for distributions of characteristic values inherent to elements in Jones-matrix images. Our choice of just these elements is related with the fact that values characterize the probability of point formation, which is related with growth of birefringence in liquid crystals at certain scales of geometric sizes. ( )xN 21;12 ( nmJ ×21;12 021;12 =J −C Depicted in Figs 3 and 4 are the results of determining the dependence (fragment (a)) and the respective spectrum of wavelet coefficients ( )xN 21;12 ( )( )xNW ba, (fragment (b)). It is seen from the data obtained that the two- dimensional array ( )( )xNW ba, is a complex coordinate- inhomogeneous and scale-dependent set of values for wavelet coefficients. Starting from this analysis, it is necessary to use a complex statistical, correlation and fractal analysis of these wavelet spectra for distributions of characteristic values in the Jones-matrix images of liquid-crystalline networks. Shown in Figs 5 and 6 is the set of coordinate ( )( )021;121, =÷== JNW mbconsta , autocorrelation ( )( )( )021;121, =÷== JNWG mbconsta and spectral dependences that characterize the spectra of wavelet coefficients for two scales 1 , log)(log −− dWF ba ( )( xNW ba, ) 14=a and 70=a of the wavelet function ba,Ψ (relation (9)) for the distributions ( )021;12 =JN corresponding to liquid- crystalline networks in saliva of healthy patient (Figs 3 and 5) and that sick with tuberculosis (Figs 4 and 6). It is seen from the data obtained that coordinate, autocorrelation and spectral dependences that characterize the sets of wavelet coefficients ( )( )021;12, =JNW ba corresponding to distributions of the amount of characteristic values in the Jones- matrix image 021;12 =J ( )nmJ ×21;12 of liquid-crystal network in the layer of saliva taken from a healthy patient and from that sick with tuberculosis are individual in every scale of a MHAT wavelet. From the quantitative viewpoint, the differences between coordinate ( )( )021;121, =÷== JNW mbconsta , autocorrelation ( )( )( )021;121, =÷== JNWG mbconsta and spectral dependences characterize 1 , log)(log −− dWF ba 231 Semiconductor Physics, Quantum Electronics & Optoelectronics, 2011. V. 14, N 2. P. 228-236. Fig. 3. Spectrum of wavelet coefficients Wa,b(N(x)) for the distribution N12;21(x) in the Jones-matrix image J12;21(m × n) corresponding to liquid-crystalline network of a saliva layer taken from a healthy patient. Fig. 4. Spectrum of wavelet coefficients Wa,b(N(x)) for the distribution N12;21(x) in the Jones-matrix image J12;21(m × n) corresponding to liquid-crystalline network of a saliva layer taken from a patient sick with tuberculosis. the values and ranges for changing the set of statistical, correlation and spectral moments of the 1-st to 4-th orders (Table 1). It is seen from the analysis of the data summarized in Table 1 that changes in values of statistical moments of the 1-st to 4-th orders, which characterize the distributions of wavelet coefficients ( )( )021;12, =ℵNW ba possess extreme values for the scale of the MHAT - function. 14=a We have ascertained the following tendencies of changes in the statistical moments of the 1-st to 4-th orders: • mean value ( )( )( )021;1214 == JNWM a increases by 1.9 times; • dispersion ( )( )( )021;1214 =σ = JNWa increases by 2.85 times; • skewness ( )( )( )021;1214 == JNWA a increases by 3.2 times; © 2011, V. Lashkaryov Institute of Semiconductor Physics, National Academy of Sciences of Ukraine 232 Semiconductor Physics, Quantum Electronics & Optoelectronics, 2011. V. 14, N 2. P. 228-236. a Wa,b(N(J12;21= 0)) G(Wa,b(N(J12;21= 0))) 1 , log)(log −− dWF ba 14=a 70=a Fig. 5. Coordinate (left column), autocorrelation (central column) and spectral (right column) dependences that characterize the spectrum of wavelet coefficients Wa,b(N(J12;21= 0)) for the distribution of characteristic values in the Jones-matrix image J12;21(m × n) of liquid-crystal network in the layer of saliva taken from a healthy patient. See explanations in the text. a Wa,b(N(J12;21= 0)) G(Wa,b(N(J12;21= 0))) 1 , log)(log −− dWF ba 14=a 14=a Fig. 6. Coordinate (left column), autocorrelation (central column) and spectral (right column) dependences that characterize the spectrum of wavelet coefficients Wa,b(N(J12;21= 0)) for the distribution of characteristic values in the Jones-matrix image J12;21(m × n) of liquid-crystal network in the layer of saliva taken from a patient sick with tuberculosis. See explanations in the text. • excess ( )( )( )021;1214 == JNWE a increases by 3.85 times. For the set of correlation moments of the 1-st to 4- th orders that characterize the autocorrelation dependences 4;3;2;1=iK ( )( )( ) © 2011, V. Lashkaryov Institute of Semiconductor Physics, National Academy of Sciences of Ukraine 021;1214 == JNWG a s of distributions for wavelet coefficient ( )( )021;12, =JNW ba on the scale of the MHAT-function for the samples of saliva taken from the patients sick with tuberculosis, we have found the following tendencies of changes in values: 14=a • correlation moment of the 1-st order K1 does not practically change; • correlation moment of the 2-nd order K2 increases by 2.3 times; • correlation moment of the 3-rd order K3 increases by 1.8 times; 233 Semiconductor Physics, Quantum Electronics & Optoelectronics, 2011. V. 14, N 2. P. 228-236. Table 1. Statistical (M; σ; A; E), correlation (Ki = 1;2;3;4), spectral (Si = 1;2;3;4) moments of the 1-st to 4-th orders for various- scale (a) distributions of wavelet coefficients Wa,b(N(J12;21= 0)) for the amount of characteristic values in Jones-matrix images corresponding to liquid-crystal network in saliva of healthy (q = 18) and sick with tuberculosis (q = 17) patients. State Norm Tuberculosis a 14=a 70=a 14=a 70=a M 0.086 ± 0.018 0.26 ± 0.051 0.12 ± 0.034 0.37 ± 0.073 σ 0.23 ± 0.057 0.085 ± 0.012 0.11 ± 0.026 0.11 ± 0.017 A 0.37 ± 0.075 0.13 ± 0.029 0.77 ± 0.14 0.21 ± 0.047 E 0.29 ± 0.057 0.19 ± 0.035 0.74 ± 0.17 0.24 ± 0.053 1K 1.34 ± 0.29 0.84 ± 0.19 1.23 ± 0.24 0.91 ± 0.22 2K 0.09 ± 0.02 0.16 ± 0.035 0.17 ± 0.032 0.13 ± 0.027 3K 0.84 ± 0.17 0.58 ± 0.12 1.14 ± 0.25 0.65 ± 0.21 4K 1.18 ± 0.23 0.76 ± 0.15 1.41 ± 0.29 0.87 ± 0.19 1S 0.52 ± 0.14 0.34 ± 0.072 0.49 ± 0.13 0.31 ± 0.065 2S 0.12 ± 0.025 0.11 ± 0.024 0.31 ± 0.075 0.15 ± 0.041 3S 0.41 ± 0.086 0.34 ± 0.077 0.19 ± 0.036 0.31 ± 0.073 4S 0.54 ± 0.12 0.34 ± 0.085 0.26 ± 0.061 0.29 ± 0.063 • correlation moment of the 4-th order increases by 1.75 times. 4K For the set of spectral moments of the 1-st to 4- th orders that characterize distributions of extremes in the logarithmic dependences of the power spectra for wavelet coefficients 4;3;2;1=iS ( ) 1 , log −− dWLogJ ba ( )( )021;12, =JNW ba of the amount of characteristic values in the Jones-matrix image corresponding to liquid-crystal network in saliva of patients sick with tuberculosis, we have found the following features: ( nmJ ×21;12 © 2011, V. Lashkaryov Institute of Semiconductor Physics, National Academy of Sciences of Ukraine ) • spectral moment of the 1-st order does not practically change; 1S • spectral moment of the 2-nd order increases by 2.1 times; 2S • spectral moment of the 3-rd order decreases by 2.2 times; 3S • spectral moment of the 4-th order decreases by 1.9 times. 4S The experimentally found differences in statistical, correlation and spectral moments of the 1-st to 4-th orders in ( )( )021;12, =JNW ba distributions on the certain scale ( ) of the soliton-like MHAT wavelet function can be explained by formation of additional small-scale globulin crystals with an increased level of birefringence. 14=a 6. Conclusions Thus, we have demonstrated the diagnostic efficiency of the wavelet analysis applied to distributions of the amount of characteristic values in the Jones-matrix images ( )nmJik × corresponding to liquid-crystalline networks of human saliva. Besides, we have offered the following parameters to diagnose tuberculosis: • statistical moments of the 1-st to 4-th orders that characterize spectra of wavelet coefficients ( )( )021;12, =JNW ba for distributions of the amount ( )xN 21;12 of characteristic values 021;12 =J in the Jones-matrix image ; ( )nmJ ×21;12 • correlation moments of the 2-nd to 4-th orders that characterize autocorrelation functions ( )xG Δ21;12 for the distributions ( )( )021;12, =JNW ba ; • spectral moments of the 2-nd to 4-th orders that characterize distributions of extremes in logarithmic dependences ( )[ ] ( )1 , loglog −− dWF ba for power spectra of the sets of the wavelet coefficients ( )( )021;12, =JNW . ba References 1. W.-F. Cheong, S. A. Prahl, A. J. Welch, “A Review of the Optical Properties of Biological Tissues,” 234 Semiconductor Physics, Quantum Electronics & Optoelectronics, 2011. V. 14, N 2. P. 228-236. IEEE J. Quantum Electron, Vol. 26, pp. 2166- 2185, Dec. 1990. 2. S. A. Prahl, M. 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