Amifostine can differentially modulate DNA double-strand breaks and apoptosis induced by idarubicin in normal and cancer cells
We have previously shown that amifostine differentially modulated the DNA-damaging action of idarubicin in normal and cancer cells and that the presence of p53 protein and oncogenic tyrosine kinases might play a role in this diversity. Aim: To investigate further this effect we have studied the infl...
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Datum: | 2008 |
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Hauptverfasser: | , , , |
Format: | Artikel |
Sprache: | English |
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Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
2008
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Schriftenreihe: | Experimental Oncology |
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Online Zugang: | http://dspace.nbuv.gov.ua/handle/123456789/139026 |
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Назва журналу: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
Zitieren: | Amifostine can differentially modulate DNA double-strand breaks and apoptosis induced by idarubicin in normal and cancer cells / K. Wozniak, E. Gloc, Z. Morawiec, J. Blasiak // Experimental Oncology. — 2008. — Т. 30, № 1. — С. 22–28. — Бібліогр.: 34 назв. — англ. |