The conceptual and clinical problems of paraneoplastic syndrome in oncology and internal medicine

Symptomatology of oncological diseases consists not only of local symptoms caused by the primary malignancy or its metastases, but also by general systemic signs that are not directly connected with the tumor. These symptoms are mostly associated with auto­immunity or endocrine influences. In many c...

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Bibliographic Details
Date:2015
Main Authors: Bilynsky, B.T., Dzhus, M.B., Litvinyak, R.I.
Format: Article
Language:English
Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2015
Series:Experimental Oncology
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Online Access:http://dspace.nbuv.gov.ua/handle/123456789/145460
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Journal Title:Digital Library of Periodicals of National Academy of Sciences of Ukraine
Cite this:The conceptual and clinical problems of paraneoplastic syndrome in oncology and internal medicine / B.T. Bilynsky, M.B. Dzhus, R.I. Litvinyak // Experimental Oncology. — 2015. — Т. 37, № 2. — С. С. 82-88. — Бібліогр.: 36 назв. — англ.

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Digital Library of Periodicals of National Academy of Sciences of Ukraine
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Summary:Symptomatology of oncological diseases consists not only of local symptoms caused by the primary malignancy or its metastases, but also by general systemic signs that are not directly connected with the tumor. These symptoms are mostly associated with auto­immunity or endocrine influences. In many cases, the source of paraneoplastic syndromes (PNS) is unknown. Nearly 15% of oncological patients demonstrate these syndromes but it is diagnosed much more rarely. The survey of the numerous PNS is offered. The significance of the PNS differs for oncologists and other physicians who encounter it in their practice. The reason of those differences, as well as the connection between PNS and cancer toxicity is discussed. The experience of antitoxic therapy (hemosorption, lymphosorption, enterosorption) used in our clinic in the previous years is overviewed. Key Words: cancer, diagnosis, paraneoplastic syndromes, tumor toxicosis.