Reversible Inactivation of the Dorsal Raphe Nucleus Increases Morphine-Induced Antinociception in Tolerated but not in Nontolerated Rats

We examined possible effects of the state of the dorsal raphe nucleus (DRN) on morphineinduced antinociception in morphine-tolerated and nontolerated rats. Stereotaxically, lidocaine (2%) was applied to the DRN for its reversible inactivation. On the test day, all animals received 10 mg/kg morphin...

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Date:2015
Main Authors: Sarihi, A., Heshmatian, B., Pahlevani, P., Komaki, A., Haghparast, A.
Format: Article
Language:English
Published: Інститут фізіології ім. О.О. Богомольця НАН України 2015
Series:Нейрофизиология
Online Access:http://dspace.nbuv.gov.ua/handle/123456789/148190
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Journal Title:Digital Library of Periodicals of National Academy of Sciences of Ukraine
Cite this:Reversible Inactivation of the Dorsal Raphe Nucleus Increases Morphine-Induced Antinociception in Tolerated but not in Nontolerated Rats / A. Sarihi, B. Heshmatian, P. Pahlevani, A. Komaki, A. Haghparast // Нейрофизиология. — 2015. — Т. 47, № 3. — С. 248-254. — Бібліогр.: 42 назв. — англ.

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Digital Library of Periodicals of National Academy of Sciences of Ukraine