Biological mutagenes and their role in the natural mutation process
Two sets of lethal mutations in chromosome 2 of Drosophila melanogaster have been tested for allelism: lethals induced by viruses and exogenous DNA and those found in different natural populations or arising de novo in the progeny of wild-type flies. It was concluded that the mutagenic effect of dif...
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| Datum: | 1995 |
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| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | English |
| Veröffentlicht: |
Інститут молекулярної біології і генетики НАН України
1995
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| Schriftenreihe: | Биополимеры и клетка |
| Online Zugang: | http://dspace.nbuv.gov.ua/handle/123456789/156187 |
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| Назва журналу: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Zitieren: | Biological mutagenes and their role in the natural mutation process / Yu.N. Alexandrov, M.D. Golubovsky // Биополимеры и клетка. — 1995. — Т. 11, № 5. — С. 24-27. — Бібліогр.: 10 назв. — англ. |
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Digital Library of Periodicals of National Academy of Sciences of Ukraine| Zusammenfassung: | Two sets of lethal mutations in chromosome 2 of Drosophila melanogaster have been tested for allelism: lethals induced by viruses and exogenous DNA and those found in different natural populations or arising de novo in the progeny of wild-type flies. It was concluded that the mutagenic effect of different viruses and other sources of DNA, exogenous for the host cells, is to induce single-locus and multiple mutations, which can spread throughout natural populations. Certain population-genetical consequences of the data obtained are discussed, and in particular, the position that during virus-induced mutagenesis, similar multiple chromosome lesions can occur repeatedly and independently in isolated populations of flies a result of a single mutation event. |
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