An estimate of ⁴⁷Sc photonuclear yield in a production target

⁴⁷Sc is considered as a promising beta-emitter for cancer immunotherapy. For its carrier-free production, the ⁴⁸Ti(γ,p) ⁴⁷ Sc reaction in the field of bremsstrahlung radiation of an electron accelerator can be used. On the basis of developed analytical model and a double-foil activation technique, t...

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Bibliographic Details
Date:2020
Main Authors: Dikiy, N.P., Lyashko, Yu.V., Shevchenko, V.A., Tenishev, A.Eh., Uvarov, V.L., Zakharchenko, A.A.
Format: Article
Language:English
Published: Національний науковий центр «Харківський фізико-технічний інститут» НАН України 2020
Series:Вопросы атомной науки и техники
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Online Access:http://dspace.nbuv.gov.ua/handle/123456789/194547
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Journal Title:Digital Library of Periodicals of National Academy of Sciences of Ukraine
Cite this:An estimate of ⁴⁷Sc photonuclear yield in a production target / N.P. Dikiy, Yu.V. Lyashko, V.A. Shevchenko, A.Eh. Tenishev, V.L. Uvarov, A.A. Zakharchenko // Problems of atomic science and tecnology. — 2020. — № 3. — С. 158-162. — Бібліогр.: 15 назв. — англ.

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Digital Library of Periodicals of National Academy of Sciences of Ukraine
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Summary:⁴⁷Sc is considered as a promising beta-emitter for cancer immunotherapy. For its carrier-free production, the ⁴⁸Ti(γ,p) ⁴⁷ Sc reaction in the field of bremsstrahlung radiation of an electron accelerator can be used. On the basis of developed analytical model and a double-foil activation technique, the main characteristics of the photonuclear isotope production and optimal dimensions of a production target have been established. The measured photonuclear yield of ⁴⁷Sc and dominant scandium admixtures in thin foils of natural titanium in the electron energy range of 35 to 95 MeV enabled to specify the available data on the cross-section of the ⁴⁸Ti(γ,p)⁴⁷Sc reaction. Using those results, the gross and specific activity of ⁴⁷Sc in the cylindrical titanium targets of optimal size were calculated by a simulation technique. The comparison of capacity of the photonuclear method of the ⁴⁷Sc production with other techniques is carried out.