Immortalization and malignant transformation of eucaryotic cells
This review is aimed at understanding the mechanisms of cell immortalization by different «immortalizing agents», oncogene-induced cell transformation of immortalized cells and moderate response of the advanced tumors to anticancer therapy in the light of tumor «oncogene and chromosome addiction», i...
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| Datum: | 2012 |
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| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | English |
| Veröffentlicht: |
Інститут клітинної біології та генетичної інженерії НАН України
2012
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| Schriftenreihe: | Цитология и генетика |
| Schlagworte: | |
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| Назва журналу: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Zitieren: | Immortalization and malignant transformation of eucaryotic cells / O.A. Stepanenko, V.M. Kavsan // Цитология и генетика. — 2012. — Т. 46, № 2. — С. 36-75. — Бібліогр.: 413 назв. — англ. |
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Digital Library of Periodicals of National Academy of Sciences of Ukraine| Zusammenfassung: | This review is aimed at understanding the mechanisms of cell immortalization by different «immortalizing agents», oncogene-induced cell transformation of immortalized cells and moderate response of the advanced tumors to anticancer therapy in the light of tumor «oncogene and chromosome addiction», intra-/intertumor heterogeneity, and chromosome instability. |
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