Intranuclear localization of transcription factories and immunoglobulin heavy chain gene alleles during human B-cell maturation
Immunoglobulin heavy chain (IGH) gene locus is expressed monoallelically in human B cells. Aim. To study the role of nuclear organization in regulation of the IGH expression during B-cell differentiation. Methods. Immunofluorescence in situ hybridization on 3D-preserved nuclei (3D immuno-FISH). Resu...
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| Datum: | 2016 |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | English |
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Інститут молекулярної біології і генетики НАН України
2016
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| Schriftenreihe: | Вiopolymers and Cell |
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| Назва журналу: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Zitieren: | Intranuclear localization of transcription factories and immunoglobulin heavy chain gene alleles during human B-cell maturation / A.V. Pichugin, O.V. Iarovaia, I.V. Sklyar, G. Lacombe, S.V. Razin, T. Fest, M. Lipinski, Y.S. Vassetzky // Вiopolymers and Cell. — 2016. — Т. 32, № 3. — С. 179-183. — Бібліогр.: 18 назв. — англ. |