Current approaches to improve the anticancer chemotherapy with alkylating agents: state of the problem in world and Ukraine
Alkylating agents are frequently used in many established anticancer chemotherapies. They alkylate the genomic DNA at various sites. Alkylation of the guanine at the O6-position is cytotoxic, it has the strongest mutagenic potential, as well as can cause the tumor development. Alkyl groups at the O6...
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| Datum: | 2012 |
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| 1. Verfasser: | |
| Format: | Artikel |
| Sprache: | English |
| Veröffentlicht: |
Інститут молекулярної біології і генетики НАН України
2012
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| Schriftenreihe: | Вiopolymers and Cell |
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| Назва журналу: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Zitieren: | Current approaches to improve the anticancer chemotherapy with alkylating agents: state of the problem in world and Ukraine / A.P. Iatsyshyna // Вiopolymers and Cell. — 2012. — Т. 28, № 2. — С. 83-92. — Бібліогр.: 58 назв. — англ. |