Human and bacterial DNA polymerases discriminate against 8-oxo-2'-deoxyadenosine- 5'-triphosphate
Цель. 8-оксоаденин – распространенное поврежденное основание, ассоциированное с онкологическими и нейродегенеративными заболеваниями. Оно может возникать вследствие непосредственного окисления аденина в ДНК или при включении окисленного dNTP. Методы. Разработан эффективный способ синтеза 8-оксо-2...
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Date: | 2012 |
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Main Authors: | Grin, I.R., Vasilyeva, S.V., Dovgerd, A.P., Silnikov, V.N., Zharkov, D.O. |
Format: | Article |
Language: | English |
Published: |
Інститут молекулярної біології і генетики НАН України
2012
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Series: | Вiopolymers and Cell |
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Journal Title: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
Cite this: | Human and bacterial DNA polymerases discriminate against 8-oxo-2'-deoxyadenosine- 5'-triphosphate / I.R. Grin, S.V. Vasilyeva, A.P. Dovgerd, V.N. Silnikov, D.O. Zharkov // Вiopolymers and Cell. — 2012. — Т. 28, № 4. — С. 306-309. — Бібліогр.: 13 назв. — англ. |
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