Предпосылки оптимизации метода криоконсервирования клеток костного мозга животных с аутоиммунной патологией

Предпосылки оптимизации метода криоконсервирования клеток костного мозга животных с аутоиммунной патологией

There were determined the functional characteristics of bone marrow cells (BM) in healthy animals and donors with autoimmune diseases (AID) prior to and following cryopreservation. The studies demonstrated that independently on the type of autoimmune pathology, the maximum amount of hemopoietic prec...

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Bibliographic Details
Date:2004
Main Authors: Kozlova, Yu. A., Goltsev, A. N., Dubrava, T. G., Gurina, T. M.
Format: Article
Language:English
Published: Publishing House ‘Akademperiodyka’ of the National Academy of Sciences of Ukraine; Institute for Problems of Cryobiology and Cryomedicine 2004
Subjects:
кістковий мозок
аутоімунні захворювання
КУО-ГМ
Online Access:https://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/692
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Journal Title:Problems of Cryobiology and Cryomedicine

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Problems of Cryobiology and Cryomedicine
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Summary:There were determined the functional characteristics of bone marrow cells (BM) in healthy animals and donors with autoimmune diseases (AID) prior to and following cryopreservation. The studies demonstrated that independently on the type of autoimmune pathology, the maximum amount of hemopoietic precursors of granulomonocytopoesis (CFU-GM) in BM was reached during its cryopreservation under the protection of 7% DMSO. For BM cells of intact animals the same integrity of CFU-GM was obtained when using DMSO in 10% concentration.

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