Synthesis of optically pure 3-heteroaryl-2-methylpropanoic and 3-heteroarylbutanoic acids by biocatalytic resolution
A new approach has been developed for synthesizing important compounds with potential biological activity − enantiomerically pure 3-heteroaryl-2-methylpropanoic and 3-heteroarylbutanoic acids. The kinetic dynamic enzymatic resolution methodology was applied at key synthesis stages. A dual biocatalyt...
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Date: | 2025 |
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Main Authors: | , , |
Format: | Article |
Published: |
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine
2025
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Online Access: | https://bioorganica.com.ua/index.php/journal/article/view/97 |
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Journal Title: | Ukrainica Bioorganica Acta |