Apoptosis-inducing effect of spiroaminopyrimidine analogue in NB4 leukemia cells via down-regulation of BIRC5 expression
Summary. Aim: It has been reported that spiroaminopyrimidine derivatives inhibited the growth and proliferation of various cancer cell lines. In the present study, we evaluated cytotoxic and apoptosis-inducing effects of 2,4-diamino-1,3-diazaspiro[5.5]-9-tert-butyl-2, 4-diene-5-carbonitril (9-tBAP)...
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Date: | 2023 |
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Main Authors: | , , , |
Format: | Article |
Language: | English |
Published: |
PH Akademperiodyka
2023
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Subjects: | |
Online Access: | https://exp-oncology.com.ua/index.php/Exp/article/view/2019-4-5 |
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Journal Title: | Experimental Oncology |