Prognostic factors in metastatic gastric carcinoma

Summary. Although its incidence has declined over last half-century, gastric cancer remains the second most frequent cause of cancer death in the world. The ⅔ of the patients are metastatic at diagnosis. The current study aimed to identify some determinants of survival in patients with meta...

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Дата:2023
Автори: Ben Kridis, W., Marrekchi, G., Mzali, R., Daoud, J., Khanfir, A.
Формат: Стаття
Мова:English
Опубліковано: PH Akademperiodyka 2023
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Онлайн доступ:https://exp-oncology.com.ua/index.php/Exp/article/view/2019-2-13
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Назва журналу:Experimental Oncology

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Experimental Oncology
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spelling oai:ojs2.ex.aqua-time.com.ua:article-2542023-10-11T16:41:24Z Prognostic factors in metastatic gastric carcinoma Prognostic factors in metastatic gastric carcinoma Ben Kridis, W. Marrekchi, G. Mzali, R. Daoud, J. Khanfir, A. chemotherapy, gastric cancer, metastasis, prognostic factors, survival chemotherapy, gastric cancer, metastasis, prognostic factors, survival Summary. Although its incidence has declined over last half-century, gastric cancer remains the second most frequent cause of cancer death in the world. The ⅔ of the patients are metastatic at diagnosis. The current study aimed to identify some determinants of survival in patients with metastatic gastric carcinoma. Materials and Methods: It was a retrospective study that involved 49 patients treated with palliative chemotherapy between January 2000 and December 2010. Factors included: age, gender, performance status, metastatic diagnosis onset (at diagnosis or later); specific metastatic sites, number of metastatic localizations, response to chemotherapy, and hemoglobin rate. Results: In univariate analysis, factors associated to a better survival were: metastasis at diagnosis, good performance status, response to chemotherapy and single metastatic site. Independent factors in multivariate analysis were: metastasis at diagnosis and single metastatic site. Conclusion: Our study confirmed many determinants on survival described in the literature. Summary. Although its incidence has declined over last half-century, gastric cancer remains the second most frequent cause of cancer death in the world. The ⅔ of the patients are metastatic at diagnosis. The current study aimed to identify some determinants of survival in patients with metastatic gastric carcinoma. Materials and Methods: It was a retrospective study that involved 49 patients treated with palliative chemotherapy between January 2000 and December 2010. Factors included: age, gender, performance status, metastatic diagnosis onset (at diagnosis or later); specific metastatic sites, number of metastatic localizations, response to chemotherapy, and hemoglobin rate. Results: In univariate analysis, factors associated to a better survival were: metastasis at diagnosis, good performance status, response to chemotherapy and single metastatic site. Independent factors in multivariate analysis were: metastasis at diagnosis and single metastatic site. Conclusion: Our study confirmed many determinants on survival described in the literature. PH Akademperiodyka 2023-06-05 Article Article application/pdf https://exp-oncology.com.ua/index.php/Exp/article/view/2019-2-13 10.32471/exp-oncology.2312-8852.vol-41-no-2.13283 Experimental Oncology; Vol. 41 No. 2 (2019): Experimental Oncology; 173-175 Експериментальна онкологія; Том 41 № 2 (2019): Експериментальна онкологія; 173-175 2312-8852 1812-9269 10.32471/exp-oncology.2312-8852.vol-41-no-2 en https://exp-oncology.com.ua/index.php/Exp/article/view/2019-2-13/2019-2-13 Copyright (c) 2023 Experimental Oncology https://creativecommons.org/licenses/by-nc/4.0/
institution Experimental Oncology
baseUrl_str
datestamp_date 2023-10-11T16:41:24Z
collection OJS
language English
topic chemotherapy
gastric cancer
metastasis
prognostic factors
survival
spellingShingle chemotherapy
gastric cancer
metastasis
prognostic factors
survival
Ben Kridis, W.
Marrekchi, G.
Mzali, R.
Daoud, J.
Khanfir, A.
Prognostic factors in metastatic gastric carcinoma
topic_facet chemotherapy
gastric cancer
metastasis
prognostic factors
survival
chemotherapy
gastric cancer
metastasis
prognostic factors
survival
format Article
author Ben Kridis, W.
Marrekchi, G.
Mzali, R.
Daoud, J.
Khanfir, A.
author_facet Ben Kridis, W.
Marrekchi, G.
Mzali, R.
Daoud, J.
Khanfir, A.
author_sort Ben Kridis, W.
title Prognostic factors in metastatic gastric carcinoma
title_short Prognostic factors in metastatic gastric carcinoma
title_full Prognostic factors in metastatic gastric carcinoma
title_fullStr Prognostic factors in metastatic gastric carcinoma
title_full_unstemmed Prognostic factors in metastatic gastric carcinoma
title_sort prognostic factors in metastatic gastric carcinoma
title_alt Prognostic factors in metastatic gastric carcinoma
description Summary. Although its incidence has declined over last half-century, gastric cancer remains the second most frequent cause of cancer death in the world. The ⅔ of the patients are metastatic at diagnosis. The current study aimed to identify some determinants of survival in patients with metastatic gastric carcinoma. Materials and Methods: It was a retrospective study that involved 49 patients treated with palliative chemotherapy between January 2000 and December 2010. Factors included: age, gender, performance status, metastatic diagnosis onset (at diagnosis or later); specific metastatic sites, number of metastatic localizations, response to chemotherapy, and hemoglobin rate. Results: In univariate analysis, factors associated to a better survival were: metastasis at diagnosis, good performance status, response to chemotherapy and single metastatic site. Independent factors in multivariate analysis were: metastasis at diagnosis and single metastatic site. Conclusion: Our study confirmed many determinants on survival described in the literature.
publisher PH Akademperiodyka
publishDate 2023
url https://exp-oncology.com.ua/index.php/Exp/article/view/2019-2-13
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AT mzalir prognosticfactorsinmetastaticgastriccarcinoma
AT daoudj prognosticfactorsinmetastaticgastriccarcinoma
AT khanfira prognosticfactorsinmetastaticgastriccarcinoma
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