Suboptimal molecular response to tyrosine kinase inhibition associated with acquisition of a T240A ABL1 kinase domain mutation in a patient with chronic myeloid leukemia
Over the last twenty years, chronic myeloid leukemia (CML) has come to be considered a paradigm for rationally selected, targeted inhibition of the disease-specific, BCR-ABL1 tyrosine kinase activity. However, a minor but significant numbers of patients either fail, or have suboptimal respo...
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Date: | 2023 |
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Main Authors: | , , , , |
Format: | Article |
Language: | English |
Published: |
PH Akademperiodyka
2023
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Subjects: | |
Online Access: | https://exp-oncology.com.ua/index.php/Exp/article/view/2019-1-1 |
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Journal Title: | Experimental Oncology |