Характерні зміни густини та в’язкості плазми людської крові в залежності від концентрації білків
The density and shear viscosity of human blood plasma and their dependence on the concentration of proteins (albumin, y-globulin, fibrinogen, etc.) entering the natural blood composition have been studied. The biomaterial concentration is varied by diluting the blood plasma with the isotonic aqueous...
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| Date: | 2020 |
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| Main Authors: | , , , |
| Format: | Article |
| Language: | English Ukrainian |
| Published: |
Publishing house "Academperiodika"
2020
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| Subjects: | |
| Online Access: | https://ujp.bitp.kiev.ua/index.php/ujp/article/view/2019422 |
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| Journal Title: | Ukrainian Journal of Physics |
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Ukrainian Journal of Physics| Summary: | The density and shear viscosity of human blood plasma and their dependence on the concentration of proteins (albumin, y-globulin, fibrinogen, etc.) entering the natural blood composition have been studied. The biomaterial concentration is varied by diluting the blood plasma with the isotonic aqueous solution. It is shown that a decrease in the biomaterial concentration down to 0.91 of its initial value leads to a drastic change in the plasma density and to a change in the character of the concentration dependence of the shear viscosity of blood plasma. A hypothesis is put forward that the observed changes in the density and shear viscosity result from the structural transformations induced by oligomerization processes; first of all, by the albumin dimerization. A conclusion is drawn that the introduced blood substitutes should not exceed 10% of the blood mass; otherwise, structural transformations of a biomaterial in blood plasma can be provoked. |
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