Sensitivity of human lymphocytes to genotoxic effect of N-methyl-N-nitrosourea: possible relation to gynecological cancers

The aim of this work is to study responses of PHA-stimulated and resting lymphocytes to methylating agent N-methyl-N-nitrosourea (MNU) and to compare sensitivity to this agent of healthy donor lymphocytes and lymphocytes from patients with gynecological cancers. Methods: Cytotoxicity of MNU, apoptot...

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Datum:2006
Hauptverfasser: Tronov, V.A., Kramarenko, I.I., Kozlova, A.D., Dederer, L.J., Kedrova, A.G., Gorbacheva, L.B.
Format: Artikel
Sprache:English
Veröffentlicht: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2006
Schriftenreihe:Experimental Oncology
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Online Zugang:http://dspace.nbuv.gov.ua/handle/123456789/137585
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Назва журналу:Digital Library of Periodicals of National Academy of Sciences of Ukraine
Zitieren:Sensitivity of human lymphocytes to genotoxic effect of N-methyl-N-nitrosourea: possible relation to gynecological cancers / V.A. Tronov, I.I. Kramarenko, A.D. Kozlova, L.J. Dederer, A.G. Kedrova, L.B. Gorbacheva // Experimental Oncology. — 2006. — Т. 28, № 4. — С. 314-318. — Бібліогр.: 22 назв. — англ.

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