Autogeneic RNA-electroporated CD40-ligand activated B-cells from hepatocellular carcinoma patients induce CD8+ T-cell responses ex vivo

Autogeneic RNA-electroporated CD40-ligand activated B-cells from hepatocellular carcinoma patients induce CD8+ T-cell responses ex vivo

Since dendritic cells (DCs) constitute only 0.1–0.5% of human peripheral blood mononuclear cells (PBMCs), and generation of DCs from monocytes or stem cells is difficult and expensive, we choose B-lymphocytes as an alternative, cost-effective source of antigen presenting cells (APC). Aim: To induce...

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Datum:2007
Hauptverfasser: Shen, S., Xu, Z., Qian, X., Ding, Y., Yu, L., Liu, B.
Format: Artikel
Sprache:English
Veröffentlicht: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2007
Schriftenreihe:Experimental Oncology
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Online Zugang:http://dspace.nbuv.gov.ua/handle/123456789/138573
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Назва журналу:Digital Library of Periodicals of National Academy of Sciences of Ukraine
Zitieren:Autogeneic RNA-electroporated CD40-ligand activated B-cells from hepatocellular carcinoma patients induce CD8+ T-cell responses ex vivo / S. Shen, Z. Xu, X. Qian, Y. Ding, L. Yu, B. Liu // Experimental Oncology. — 2007. — Т. 29, № 2. — С. 137-143. — Бібліогр.: 49 назв. — англ.

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