Ascorbate depletion increases growth and metastasis of melanoma cells in vitamin C deficient mice
Aim: Our main objective was to determine the effect of ascorbate supplementation in mice unable to synthesize ascorbic acid (gulo KO) when challenged with murine B16FO cancer cells. Methods: Gulo KO female mice 36–40 weeks of age were deprived of or maintained on ascorbate in food and water for 4 we...
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| Date: | 2011 |
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| Main Authors: | , , , , , |
| Format: | Article |
| Language: | English |
| Published: |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
2011
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| Series: | Experimental Oncology |
| Subjects: | |
| Online Access: | http://dspace.nbuv.gov.ua/handle/123456789/138671 |
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| Journal Title: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Cite this: | Ascorbate depletion increases growth and metastasis of melanoma cells in vitamin C deficient mice / J. Cha, M.W. Roomi, V. Ivanov, T. Kalinovsky, A. Niedzwiecki, M. Rath // Experimental Oncology. — 2011. — Т. 33, № 4. — С. 226-230. — Бібліогр.: 20 назв. — англ. |