17-AAG mediates targeting of HSP90 limits tert activity in peritoneal sarcoma related malignant ascites by downregulating cyclin D1 during cell cycle entry

17-AAG mediates targeting of HSP90 limits tert activity in peritoneal sarcoma related malignant ascites by downregulating cyclin D1 during cell cycle entry

Aim: Peritoneal or retro-peritoneal sarcomatosis related malignant ascites formation is a rare but serious consequence of the locoregional metastatic event. The present work aimed to study the effect of the Hsp90 inhibitor (17-AAG), an ansamycin analog, on cell cycle and DNA replication specific cha...

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Datum:2012
Hauptverfasser: Chaklader, M., Das, P., Pereira, J.A., Law, A., Chattopadhyay, S., Chatterjee, R., Mondal, A., Law, S.
Format: Artikel
Sprache:English
Veröffentlicht: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2012
Schriftenreihe:Experimental Oncology
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Online Zugang:http://dspace.nbuv.gov.ua/handle/123456789/138688
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Назва журналу:Digital Library of Periodicals of National Academy of Sciences of Ukraine
Zitieren:17-AAG mediates targeting of HSP90 limits tert activity in peritoneal sarcoma related malignant ascites by downregulating cyclin D1 during cell cycle entry / M. Chaklader, P. Das, J.A. Pereira, A. Law, S. Chattopadhyay, R. Chatterjee, A. Mondal, S. Law // Experimental Oncology. — 2012. — Т. 34, № 2. — С. 90-96. — Бібліогр.: 24 назв. — англ.

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