Accelerated rejection of the second transplants of immunogenic tumor in mice under inhibition of indoleamine 2,3-dioxygenase activity by ethyl pyruvate
Aim: A recently discovered enzyme, indoleamine 2,3-dioxygenase (IDO), is expressed in placenta, dendritic cells and also in many kinds of tumors and in tumor-infiltrating macrophages. By catabolizing tryptophan, IDO causes local depletion of this essential amino acid and excess of kinurenin, and sup...
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| Date: | 2012 |
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| Main Authors: | , , , , , |
| Format: | Article |
| Language: | English |
| Published: |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
2012
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| Series: | Experimental Oncology |
| Subjects: | |
| Online Access: | http://dspace.nbuv.gov.ua/handle/123456789/138692 |
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| Journal Title: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Cite this: | Accelerated rejection of the second transplants of immunogenic tumor in mice under inhibition of indoleamine 2,3-dioxygenase activity by ethyl pyruvate / E.D. Vasilyeva, V. Kaledin, V.P. Nicolin, N.A. Popova, I.A. Kirilyuk, I.A. Grigor`ev // Experimental Oncology. — 2012. — Т. 34, № 1. — С. 66-68. — Бібліогр.: 14 назв. — англ. |