Intrinsic defect in B-lymphoblastoid cell lines from patients with X-linked lymphoproliferative disease type 1. I. Cell surface phenotype and functional studies

Intrinsic defect in B-lymphoblastoid cell lines from patients with X-linked lymphoproliferative disease type 1. I. Cell surface phenotype and functional studies

Background: Mutations in SH2D1A/DSHP/SAP gene are responsible for the onset of X-linked lymphoproliferative disease type 1 (XLP1) that have increased risk for B-cell lymphoma development. In XLP1 patients SAP deficient NK, NKT and CD8+ cytotoxic T cells are inefficient in eliminating EBV-infected pr...

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Date:2014
Main Authors: Shlapatska, L.M., Kovalevska, L.M., Gordiienko, I.M., Sidorenko, S.P.
Format: Article
Language:English
Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2014
Series:Experimental Oncology
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Online Access:http://dspace.nbuv.gov.ua/handle/123456789/145311
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Journal Title:Digital Library of Periodicals of National Academy of Sciences of Ukraine
Cite this:Intrinsic defect in B-lymphoblastoid cell lines from patients with X-linked lymphoproliferative disease type 1. I. Cell surface phenotype and functional studies / L.M. Shlapatska, L.M. Kovalevska, I.M. Gordiienko, S.P. Sidorenko // Experimental Oncology. — 2014. — Т. 36, № 1. — С. 2-8. — Бібліогр.: 52 назв. — англ.

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Digital Library of Periodicals of National Academy of Sciences of Ukraine

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