Intrinsic defect in B-lymphoblastoid cell lines from patients with X-linked lymphoproliferative disease type 1. II. Receptor-mediated Akt/PKB and ERK1/2 activation and transcription factors expression profile

Background: X-linked lymphoproliferative disease type 1 (XLP1) belongs to genetically determined primary immunodeficiency syndromes with mutations in SH2D1A/DSHP/SAP gene. The dramatic increase of the risk of B-cell lymphoma development in XLP1 patients is linked not only to SAP deficiency of NK, NK...

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Datum:2014
Hauptverfasser: Shlapatska, L.M., Kovalevska, L.M., Gordiienko, I.M., Sidorenko, S.P.
Format: Artikel
Sprache:English
Veröffentlicht: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2014
Schriftenreihe:Experimental Oncology
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Online Zugang:http://dspace.nbuv.gov.ua/handle/123456789/145360
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Назва журналу:Digital Library of Periodicals of National Academy of Sciences of Ukraine
Zitieren:Intrinsic defect in B-lymphoblastoid cell lines from patients with X-linked lymphoproliferative disease type 1. II. Receptor-mediated Akt/PKB and ERK1/2 activation and transcription factors expression profile / L.M. Shlapatska, L.M. Kovalevska, I.M. Gordiienko, S.P. Sidorenko // Experimental Oncology. — 2014. — Т. 36, № 3. — С. 162-169. — Бібліогр.: 51 назв. — англ.

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