Caffeine Suppresses GABA Receptor-Mediated Current in Rat Primary Sensory Neurons Via Inhibition of Intracellular Phosphodiesterase

In acutely isolated rat primary sensory neurons, the effects of caffeine on GABA receptormediated current (IGABA) were investigated using a whole-cell patch clamp technique. We found that applications of GABA (10-1000 µM) induced inward currents in a concentration-dependent manner; the currents ma...

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Bibliographic Details
Date:2015
Main Authors: Yang, J.Y., Yang, G., Ren, J., Zhao, J., Li Sh.
Format: Article
Language:English
Published: Інститут фізіології ім. О.О. Богомольця НАН України 2015
Series:Нейрофизиология
Online Access:http://dspace.nbuv.gov.ua/handle/123456789/148186
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Journal Title:Digital Library of Periodicals of National Academy of Sciences of Ukraine
Cite this:Caffeine Suppresses GABA Receptor-Mediated Current in Rat Primary Sensory Neurons Via Inhibition of Intracellular Phosphodiesterase / J.Y. Yang, G. Yang, J. Ren, J. Zhao, Sh. Li // Нейрофизиология. — 2015. — Т. 47, № 2. — С. 129-135. — Бібліогр.: 25 назв. — англ.

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Digital Library of Periodicals of National Academy of Sciences of Ukraine