Heterozygous deletions are main cause of expression alterations of PPM1M and PRICLE2 genes in human clear cell renal cell carcinomas
Aim. To discover the mechanisms of the PPM1M and PRICKLE2 genes expression alterations in clear cell renal cell carcinomas. Methods. Study of the copy number was performed, using the quantitative PCR (Q-PCR). Results. Deletions of PPM1M were found in 55 % of cases, amplifications – in 17 % and in 28...
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| Date: | 2015 |
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| Main Authors: | , , , , , |
| Format: | Article |
| Language: | English |
| Published: |
2015
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| Subjects: | |
| Online Access: | http://dspace.nbuv.gov.ua/handle/123456789/152430 |
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| Journal Title: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Cite this: | Heterozygous deletions are main cause of expression alterations of PPM1M and PRICLE2 genes in human clear cell renal cell carcinomas / E.E. Rudenko, Y.V. Lapska, G.V. Gerashchenko, E.O. Stakhovsky, M.V. Vikarchuk, V.I. Kashuba // Biopolymers and Cell. — 2015. — Т. 31, № 1. — С. 29-33 . — Бібліогр.: 21 назв. — англ. |