Aberrant DNA glycosylase-initiated repair pathway of free radicals in-duced DNA damage: implications for age-related diseases and natural aging

Aerobic cellular respiration generates reactive oxygen species (ROS), which can damage macro-molecules including lipids, proteins and DNA. It was proposed that aging is a consequence of accumulation of naturally occurring unrepaired oxidative DNA damage. In human cells, approximately 2000 to 8000 DN...

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Bibliographic Details
Date:2017
Main Authors: Matkarimov, B.T., Saparbaev, M.K.
Format: Article
Language:English
Published: Інститут молекулярної біології і генетики НАН України 2017
Series:Вiopolymers and Cell
Subjects:
Online Access:http://dspace.nbuv.gov.ua/handle/123456789/152878
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Journal Title:Digital Library of Periodicals of National Academy of Sciences of Ukraine
Cite this:Aberrant DNA glycosylase-initiated repair pathway of free radicals in-duced DNA damage: implications for age-related diseases and natural aging / B.T. Matkarimov, M.K. Saparbaev // Вiopolymers and Cell. — 2017. — Т. 33, № 1. — С. 3-23. — Бібліогр.: 118 назв. — англ.

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Digital Library of Periodicals of National Academy of Sciences of Ukraine