Synthesis and biological evaluation of novel amino-substituted derivatives of pyrido[2,3-d]pyrimidine as inhibitors of protein kinase CK2

Aim. A search for human protein kinase CK2 inhibitors in a series of new amino-substituted pyrido[2,3-d]pyrimidine derivatives. Methods. Organic synthesis, analytical and spectral methods, molecular docking, in vitro biochemical testing. Results. Synthesis of new pyrido[2,3-d]pyrimidine derivatives...

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Datum:2017
Hauptverfasser: Zinchenko, A.N., Muzychka, L.V., Smolii, O.B., Bdzhola, V.G., Protopopov, M.V., Yarmoluk, S.M.
Format: Artikel
Sprache:English
Veröffentlicht: Інститут молекулярної біології і генетики НАН України 2017
Schriftenreihe:Вiopolymers and Cell
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Online Zugang:http://dspace.nbuv.gov.ua/handle/123456789/152990
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Назва журналу:Digital Library of Periodicals of National Academy of Sciences of Ukraine
Zitieren:Synthesis and biological evaluation of novel amino-substituted derivatives of pyrido[2,3-d]pyrimidine as inhibitors of protein kinase CK2 / A.N. Zinchenko, L.V. Muzychka, O.B. Smolii, V.G. Bdzhola, M.V. Protopopov, S.M. Yarmoluk // Вiopolymers and Cell. — 2017. — Т. 33, № 5. — С. 367-378. — Бібліогр.: 41 назв. — англ.

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