The mechanisms of activation of the single chain cytokine receptors: preformed and ligand-induced dimerization
Despite intensive studies, the mechanisms of cytokine receptor activation are still not completely understood. Historically two models have been proposed: early studies suggested a mechanism involving ligand-induced di- merization of the receptors which results in the activation of downstream signal...
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Date: | 2014 |
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Main Authors: | , , |
Format: | Article |
Language: | English |
Published: |
Інститут молекулярної біології і генетики НАН України
2014
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Series: | Вiopolymers and Cell |
Subjects: | |
Online Access: | http://dspace.nbuv.gov.ua/handle/123456789/154300 |
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Journal Title: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
Cite this: | The mechanisms of activation of the single chain cytokine receptors: preformed and ligand-induced dimerization / V.S. Gryshkova, R.I. Albu, S.N. Constatinescu // Вiopolymers and Cell. — 2014. — Т. 30, № 3. — С. 184-189. — Бібліогр.: 53 назв. — англ. |