Signaling pathways involved in apoptosis induced by novel angucycline antibiotic landomycin E in Jurkat T-leukemia cells
Aim. To study the molecular mechanisms of action of novel anticancer antibiotic landomycin E (LE). Methods. Annexin V/propidium iodide, DAPI (4',6-diamidino-2-phenylindole) staining, Western-blot analysis. Results. LE applied in 2 µg/ml dose (IC50), induced reactive oxygen species (ROS)-depend...
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| Date: | 2011 |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Інститут молекулярної біології і генетики НАН України
2011
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| Series: | Вiopolymers and Cell |
| Subjects: | |
| Online Access: | http://dspace.nbuv.gov.ua/handle/123456789/156386 |
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| Journal Title: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Cite this: | Signaling pathways involved in apoptosis induced by novel angucycline antibiotic landomycin E in Jurkat T-leukemia cells / R.R. Panchuk // Вiopolymers and Cell. — 2011. — Т. 27, № 2. — С. 124-131. — Бібліогр.: 26 назв. — англ. |