The new base excision repair pathway in mammals mediated by tyrosyl-DNA-phosphodiesterase 1

Human tyrosyl-DNA phosphodiesterase 1 (Tdp1) hydrolyzesthe phosphodiester bond at a DNA 3' end linked to a tyrosyl moiety and has been implicated in the repair of Topoisomerase I (TopI )-DNA covalent complexes. Tdp1 can also hydrolyze other 3' end DNA alterations including 3' phosphog...

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Bibliographic Details
Date:2012
Main Authors: Lebedeva, N.A., Rechkunova, N.I., Lavrik, O.I.
Format: Article
Language:English
Published: Інститут молекулярної біології і генетики НАН України 2012
Series:Вiopolymers and Cell
Subjects:
Online Access:http://dspace.nbuv.gov.ua/handle/123456789/156841
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Journal Title:Digital Library of Periodicals of National Academy of Sciences of Ukraine
Cite this:The new base excision repair pathway in mammals mediated by tyrosyl-DNA-phosphodiesterase 1 / N.A. Lebedeva, N.I. Rechkunova, O.I. Lavrik // Вiopolymers and Cell. — 2012. — Т. 28, № 3. — С. 202-206. — Бібліогр.: 36 назв. — англ.

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Digital Library of Periodicals of National Academy of Sciences of Ukraine