The new base excision repair pathway in mammals mediated by tyrosyl-DNA-phosphodiesterase 1
Human tyrosyl-DNA phosphodiesterase 1 (Tdp1) hydrolyzesthe phosphodiester bond at a DNA 3' end linked to a tyrosyl moiety and has been implicated in the repair of Topoisomerase I (TopI )-DNA covalent complexes. Tdp1 can also hydrolyze other 3' end DNA alterations including 3' phosphog...
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Date: | 2012 |
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Main Authors: | , , |
Format: | Article |
Language: | English |
Published: |
Інститут молекулярної біології і генетики НАН України
2012
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Series: | Вiopolymers and Cell |
Subjects: | |
Online Access: | http://dspace.nbuv.gov.ua/handle/123456789/156841 |
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Journal Title: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
Cite this: | The new base excision repair pathway in mammals mediated by tyrosyl-DNA-phosphodiesterase 1 / N.A. Lebedeva, N.I. Rechkunova, O.I. Lavrik // Вiopolymers and Cell. — 2012. — Т. 28, № 3. — С. 202-206. — Бібліогр.: 36 назв. — англ. |