In silico analysis of the structure of variable domains of mouse single-chain antibodies specific to the human recombinant interferon β1b

In silico analysis of the DNA encoding singlechain Fv antibodies (ScFv) specific to the human recombinant interferon β1b and α2b (rhIFNβ1b, rhIFNα2b) has been carried out. The V, D and J-gene segments, the complementaritydetermining (CDR) and framework (FR) regions, n-nucleotides as well as mutation...

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Bibliographic Details
Date:2009
Main Authors: Flyak, A.I., Pavlova, M.V., Gilchuk, P.V.
Format: Article
Language:English
Published: Інститут клітинної біології та генетичної інженерії НАН України 2009
Series:Цитология и генетика
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Online Access:http://dspace.nbuv.gov.ua/handle/123456789/66623
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Journal Title:Digital Library of Periodicals of National Academy of Sciences of Ukraine
Cite this:In silico analysis of the structure of variable domains of mouse single-chain antibodies specific to the human recombinant interferon β1b / A.I. Flyak, M.V. Pavlova, P.V. Gilchuk // Цитология и генетика. — 2009. — Т. 43, № 1. — С. 54-60. — Бібліогр.: 19 назв. — англ.

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Digital Library of Periodicals of National Academy of Sciences of Ukraine