Towards a Medically Approved Technology for Large-Scale Stem Cell Banks: Tools and Method

Towards a Medically Approved Technology for Large-Scale Stem Cell Banks: Tools and Method

The importance, of the development of stem cell cryobanking has increased recently with an augmentation of stem cell research and its therapeutic applications. The development of therapies is, among other things, limited by high sensitivity of stem cells to freezingthawing procedures. Thus, new appr...

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Bibliographic Details
Date:2008
Main Authors: Katsen-Globa, A., Schulz, J.C., Baunach, J.S., Ehrhart, F., Oh, Y.-J., Schön, U., Kofanova, O., Beier, A.F.J., Wiedemeier, S., Metze, J., Shirley, S., Spitkovsky, D., Sachinidis, A., Hescheler, J., Zimmermann, H.
Format: Article
Language:English
Published: Інститут проблем кріобіології і кріомедицини НАН України 2008
Series:Проблемы криобиологии и криомедицины
Subjects:
Секция «Современные проблемы выделения, культивирования, дифференциации и криоконсервирования стволовых клеток. Клеточная и тканевая терапия»
Online Access:http://dspace.nbuv.gov.ua/handle/123456789/69070
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Journal Title:Digital Library of Periodicals of National Academy of Sciences of Ukraine
Cite this:Towards a Medically Approved Technology for Large-Scale Stem Cell Banks: Tools and Method / A. Katsen-Globa, J.C. Schulz, J.S. Baunach, F. Ehrhart, Y.-J. Oh, U. Schön, O. Kofanova, A.F.J. Beier, S. Wiedemeier, J. Metze, S. Shirley, D. Spitkovsky, A. Sachinidis, J. Hescheler, H. Zimmermann // Проблемы криобиологии. — 2008. — Т. 18, № 4. — С. 468-478. — Бібліогр.: 43 назв. — англ.

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Digital Library of Periodicals of National Academy of Sciences of Ukraine
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Summary:The importance, of the development of stem cell cryobanking has increased recently with an augmentation of stem cell research and its therapeutic applications. The development of therapies is, among other things, limited by high sensitivity of stem cells to freezingthawing procedures. Thus, new approaches are needed for preservation and related evaluation methods, as well as new technologies for long term storage of large numbers of stem cells. Here we present selected recent improvements of stem cell cryopreservation, e.g. for freezing of adherent human embryonic stem cells using gel-like matrices. We report the application and performance of novel microsystem-based cryosubstrates and devices and describe new evaluation methods and the results of a thermal stress cycle study.

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