α,α-Difluoro-β-ketophosphonates on a tetraazamacrocyclic platform: Synthesis and inhibitory activity against protein tyrosine phosphatases
The present study offers a new approach for designing inhibitors of protein tyrosine phosphatases. We have synthesized the cyclam derivatives with α,α-difluoro-β-ketophosphonate fragments covalently attached to tetraazamacrocyclic scaffold, which is known to be of medical interest. The obtained fu...
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| Date: | 2014 |
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| Main Authors: | , , , , , , , , |
| Format: | Article |
| Language: | English |
| Published: |
Видавничий дім "Академперіодика" НАН України
2014
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| Series: | Доповіді НАН України |
| Subjects: | |
| Online Access: | http://dspace.nbuv.gov.ua/handle/123456789/88260 |
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| Journal Title: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Cite this: | α,α-Difluoro-β-ketophosphonates on a tetraazamacrocyclic platform: Synthesis and inhibitory activity against protein tyrosine phosphatases / D.I. Khavrienko, O.L. Kobzar, M.V. Shevchuk, V.D. Romanenko, S.M. Kobelev, A.D. Averin, I.P. Beletskaya, A.I. Vovk, V.P. Kukhar // Доповiдi Нацiональної академiї наук України. — 2014. — № 9. — С. 109-115. — Бібліогр.: 15 назв. — англ. |