Clinical impact of MDR1-expression in testicular germ cell cancer

Aim: The multidrug resistance protein 1 (MDR1, P-gp, p-170) is a membrane glycoprotein that acts as an energy-dependent drug efflux pump. In various malignancies its expression is associated with resistance to diverse cytostatic drugs, and therefore predicts resistance to systemic treatment. The aim...

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Date:2007
Main Authors: Schrader, A.J., Seger, M., Konrad, L., Olbert, P., Hegele, A., Hofmann, R., Heidenreich, A.
Format: Article
Language:English
Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2007
Series:Experimental Oncology
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Journal Title:Digital Library of Periodicals of National Academy of Sciences of Ukraine
Cite this:Clinical impact of MDR1-expression in testicular germ cell cancer / A. J. Schrader, M. Seger, L. Konrad, P. Olbert, A. Hegele, R. Hofmann, A. Heidenreich // Experimental Oncology. — 2007. — Т. 29, № 3. — С. 212–216. — Бібліогр.: 22 назв. — англ.

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Digital Library of Periodicals of National Academy of Sciences of Ukraine

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