Synthesis and evaluation of antitumor activity of some thiazolo[4,5-b]pyridines

Aim. To synthesize a series of novel 3H-thiazolo[4,5-b]pyridine-2-ones by structural modification of the core heterocycle in its N3- and N6-positions and to evaluate their anticancer activity in vitro on several tumor cell lines. Methods. Organic synthesis, 1 H-NMR spectroscopy, trypan blue cell v...

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Datum:2012
Hauptverfasser: Chaban, T.I., Panchuk, R.R., Klenina, O.V., Skorokhyd, N.R., Ogurtsov, V.V., Chaban, I.G.
Format: Artikel
Sprache:English
Veröffentlicht: Інститут молекулярної біології і генетики НАН України 2012
Schriftenreihe:Вiopolymers and Cell
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Назва журналу:Digital Library of Periodicals of National Academy of Sciences of Ukraine
Zitieren:Synthesis and evaluation of antitumor activity of some thiazolo[4,5-b]pyridines / T.I. Chaban, R.R. Panchuk, O.V. Klenina, N.R. Skorokhyd, V.V. Ogurtsov, I.G. Chaban // Вiopolymers and Cell. — 2012. — Т. 28, № 5. — С. 389-396. — Бібліогр.: 18 назв. — англ.

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