Особенности выделения, криоконсервирования и аллогенной трансплантации гепатоцитов кроликов

The effect of introduction rate of hepatocyte suspension into a portal vein on transaminase activity in blood and liver morphology was studied. The obtained results have demonstrated, that the rate decrease of hepatocyte introduction when transplanting into a portal vein results in an even distribut...

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Bibliographic Details
Date:2003
Main Authors: Lebedinsky, A. S., Petrenko, A. Yu.
Format: Article
Language:English
Published: Publishing House ‘Akademperiodyka’ of the National Academy of Sciences of Ukraine; Institute for Problems of Cryobiology and Cryomedicine 2003
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Online Access:https://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/1010
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Journal Title:Problems of Cryobiology and Cryomedicine

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Problems of Cryobiology and Cryomedicine
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Summary:The effect of introduction rate of hepatocyte suspension into a portal vein on transaminase activity in blood and liver morphology was studied. The obtained results have demonstrated, that the rate decrease of hepatocyte introduction when transplanting into a portal vein results in an even distribution of donor’s hepatocytes to recipient’s liver, allowing to reduce the thrombogenesis in the portal blood flow system and to decrease the damage degree for recipient’s own liver. The results can be used for studying the effect of transplanted cryopreserved hepatocytes at experimental pathologies of rabbit’s liver.