5-Заміщені N-(9Н-пурин-6-іл)-1,2-оксазол-3-карбоксаміди як інгібітори ксантиноксидази

Synthetic 6-substituted purine derivatives are known to exhibit diverse bioactivity. In this paper, a series of N-(9H-purin-6-yl)-1,2-oxazole-3-carboxamide derivatives were synthesized and evaluated in vitro against xanthine oxidase, an enzyme of purine catabolism. The introduction of aryl substitue...

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Datum:2020
Hauptverfasser: Muzychka, Oksana V., Kobzar, Oleksandr L., Shablykin, Oleh V., Brovarets, Volodymyr S., Vovk, Andriy I.
Format: Artikel
Sprache:English
Veröffentlicht: V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine 2020
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Online Zugang:https://bioorganica.com.ua/index.php/journal/article/view/4
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Назва журналу:Ukrainica Bioorganica Acta

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Ukrainica Bioorganica Acta