Design, synthesis and structural characterization of coumarin-1,3,4-thiadiazole hybrids bearing (cyclo)alkyl and phenyl substituents: expanding the chemical space for medicinal chemistry
The rational expansion of chemical space through molecular hybridization is a key strategy in the discovery of novel bioactive scaffolds. In this study, we report the synthesis and structural characterization of a new series of hybrid molecules combining coumarin and 1,3,4-thiadiazole frameworks, be...
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| Дата: | 2025 |
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| Автори: | , , |
| Формат: | Стаття |
| Опубліковано: |
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine
2025
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| Онлайн доступ: | https://bioorganica.com.ua/index.php/journal/article/view/95 |
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| Назва журналу: | Ukrainica Bioorganica Acta |