Design, synthesis and structural characterization of coumarin-1,3,4-thiadiazole hybrids bearing (cyclo)alkyl and phenyl substituents: expanding the chemical space for medicinal chemistry

Design, synthesis and structural characterization of coumarin-1,3,4-thiadiazole hybrids bearing (cyclo)alkyl and phenyl substituents: expanding the chemical space for medicinal chemistry

The rational expansion of chemical space through molecular hybridization is a key strategy in the discovery of novel bioactive scaffolds. In this study, we report the synthesis and structural characterization of a new series of hybrid molecules combining coumarin and 1,3,4-thiadiazole frameworks, be...

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Datum:2025
Hauptverfasser: Rybina, Yelyzaveta Y., Moskvina, Viktoriia S., Khilya, Volodymyr
Format: Artikel
Veröffentlicht: V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine 2025
Online Zugang:https://bioorganica.com.ua/index.php/journal/article/view/95
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Назва журналу:Ukrainica Bioorganica Acta

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Ukrainica Bioorganica Acta

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