Conjugation of new DNA vaccine with polyethylenimine induces cellular immune response and tumor regression in neuroblastoma mouse model

Summary. Aim: To estimate immunogenicity and antitumor effect of new DNA vaccine against neuroblastoma using tyrosine hydroxylase as an antigen and linear polyethylenimine (PEI) 20 kDa as a synthetic DNA carrier in syngeneic mouse tumor model. Materials and Methods: DNA vaccine was made by...

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Bibliographic Details
Date:2023
Main Authors: Stegantseva, M.V., Shinkevich, V.A., Tumar, E.M., Meleshko, A.N.
Format: Article
Language:English
Published: PH Akademperiodyka 2023
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Online Access:https://exp-oncology.com.ua/index.php/Exp/article/view/2020-2-11
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Journal Title:Experimental Oncology

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Experimental Oncology