Rapamycin-induced autophagy plays a pro-survival role by enhancing up-regulation of intracellular ferritin expression in acute lymphoblastic leukemia
Summary. Elevated mammalian target of rapamycin (mTOR) signaling has been reported to correlate with poor prognosis in acute lymphoblastic leukemia (ALL) patients. Rapamycin, an mTOR kinase inhibitor, and also a potent autophagy inducer, could not only effectively reverse glucocorticoid resistance,...
Saved in:
| Date: | 2023 |
|---|---|
| Main Authors: | , , , , |
| Format: | Article |
| Language: | English |
| Published: |
PH Akademperiodyka
2023
|
| Subjects: | |
| Online Access: | https://exp-oncology.com.ua/index.php/Exp/article/view/2020-1-3 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Journal Title: | Experimental Oncology |