Оптимiзацiя синтезу i спектральна характеристика нових гiдразонiв на основi 5-нiтроiндазола з фармакологiчним потенцiалом
A number of new hydrazones with biological activity are synthesized on the basis of 5-nitroindazole. The most efficient conditions of their synthesis with maximum reaction yield are established. The chemical structure of new compounds is found by the elemental analysis, FTIR spectroscopy, and 1H-NMR...
Збережено в:
| Дата: | 2018 |
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| Автори: | , , , , , , |
| Формат: | Стаття |
| Мова: | English |
| Опубліковано: |
Publishing house "Academperiodika"
2018
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| Теми: | |
| Онлайн доступ: | https://ujp.bitp.kiev.ua/index.php/ujp/article/view/2018446 |
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| Назва журналу: | Ukrainian Journal of Physics |
Репозитарії
Ukrainian Journal of Physics| Резюме: | A number of new hydrazones with biological activity are synthesized on the basis of 5-nitroindazole. The most efficient conditions of their synthesis with maximum reaction yield are established. The chemical structure of new compounds is found by the elemental analysis, FTIR spectroscopy, and 1H-NMR method. The data of spectral analysis were verified by calculations with the HyperChem software. Toxicological tests indicate that the synthesized hydrazones have the antitumor effect. |
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